Priya Sethi (Shriya Saran) indulges her infatuation with American culture by working nights (while Americans are at work, on the other side of the world) at the Citi One Bank Card call center in Mumbai, India. Speaking in a perfect American English accent, she tells her customers her name is Jennifer David and a native of San Francisco. Her conservative father Rajeev is unhappy that she is so eager to forsake her own culture for another, but will be pleased when she goes through with her arranged marriage to wealthy but childishly dull Vikram.Priya, posing as Jennifer David, happens to call the handsome and charming Granger Woodruff (Jesse Metcalfe) to help him with the fraudulent charges on his credit card. Priya and Granger have an instant connection over the phone. Unable to suppress the intrigue their easy chemistry offers, Priya agrees to meet Granger in San Francisco. When Priya goes to the meeting place, he doesn't recognize her. As she is attempting to check out of the hotel, they stumble into each other and finally meet. They immediately hit it off and he invites her out to dinner. Priya and Granger's relationship blossoms as they share a wonderfully romantic date the following day. They tour the City by the Bay by cable car, sample some especially spicy curry (much to his chagrin), and nearly -- but not quite -- kiss with the Golden Gate Bridge as a backdrop. Improbably, unthinkably, they are falling in love.However, Priya's family has arrived to bring their wayward daughter home a la Coming to America and elude the shame of her escapades. Granger struggles with himself mentally for having abandoned Jennifer David for Priya instead, but still doesn't know that the Priya and Jennifer are the same person. Meanwhile, both lovers wonder if they just might be too different for their love to actually be possible.Eventually, Priya and Granger are found out by her parents and he learns that Priya is actually Jennifer David, and also that she is engaged to Vikram. He is angry that she deceived him, and painfully decides to cut their ties. All of Priya's family is happy for the relationship to have ended, except for her 80 year-old Aunt who advises her that life is too short to live to make only others happy.Priya goes to Granger's hotel to fight for their love but is shattered when she finds his previous girlfriend in the hotel room with him. She is extremely upset that he could forget about her so easily, and he lets her leave and walk out of his life as if forever.Back in India, Priya can't bring herself to accept a lackluster life with Vikram. As she stuggles to gently disengage without hurting her family, announcing to her betrothed's family that she must develop as a person, her once-future father in law calls her a rude name. Amazingly, her father forcefully stands up for her, points out that whenever she enters a room, people smile, and that he loves her.Granger, too, feels something is missing. While giving the traditional Best Man's Toast at a wedding, he quotes the groom, his childhood best friend: "Don't let anything stand between you and your future." Shocked speechless before finishing the toast, he realizes what he may still be able to save. He rushes to the airport, furiously calling the bank in Mumbai with the help of a brainy, native New Yorker (and Hindi-speaking) cab driver.Priya has thrown herself back into her work, accepting a promotion to help her coworkers become as effective as she is channeling American attitudes and accent. Just as she is counseling a young man to control his emotions to better serve the bank and its customers, Granger strides into Priya's call center and cautiously declares his devotion. With a hundred eyes on the couple, a coworker coaxes, "Kiss him! Kiss him!" They kiss for the first time to the cheers of her crew.After her shift, as morning breaks, the apprehensive couple finds her family enjoying an open-air breakfast in their sun-dappled garden. Granger bravely attempts to win the approval of Priya's father by promising to honor her and her culture in phonetic but crude Hindi. "You are hurting my ears. Speak English, boy!" orders Father. Granger formally repeats his commitment to respect and care for her. Father thinks it over for a few moments as the family watches him intently, and he graciously accepts the young man, welcoming him to breakfast.