Dr. Miles J. Bennell returns from a convention to the small town Santa Mira and is welcomed by his nurse and friend Sally Withers at the train station. She reports that several patients had come to see him while he was traveling. While driving to his office with Sally, Miles stops the car when a boy runs into the road. Soon he learns that the boy insists that his mother is not actually her, then he meets in his office his former girlfriend Becky Driscoll, who has just divorced and returned from England. Becky tells that her cousin Wilma Lentz insists that her Uncle Ira is not him. Miles invites Becky to have dinner with him and he meets his friend, the psychiatrist Dr. Dan 'Danny' Kauffman (Larry Gates) who reveals that the population of Santa Mira is paranoid with mass hysteria, imagining doubles of their relatives. Miles and Becky go to a restaurant and Miles receives a phone call from his friend Jack Belicec asking him to go to his house. Miles and Becky visit Jack and his wife Theodora 'Teddy' Belicec and they show a partially developed body with Jack's characteristics on the pool table and they go to Miles' house. Then Miles goes to Becky's house and finds a body identical to her in the basement. Miles brings Becky to his house and in the morning, the group finds seedpods with doubles of them. Soon they discover that the population is being replaced by emotionless doubles while asleep. They unsuccessfully try to contact the authorities in other cities and discover that they are under siege by the pod people. Will they have the chance to flee from Santa Mira?—Claudio Carvalho, Rio de Janeiro, Brazil