In "Fullmetal Alchemist (2017)", Alphonse (Atom Mizuishi) and Edward (Ryosuke Yamadalost) their mother and their dear friend Captain Hughes. Dr. Marcoh had headed the Homunculus experiments with the help of the Philosopher's Stone under the orders of the State. He conducted these experiments inside Laboratory No. 5, disguised as a prison. The Stone was derived from torturing countless prisoners and was finally laid off as an invalid experiment. However, Marcoh was killed by Homunculi while he was giving the information and hints to Ed and Winry (Tsubasa Honda). With the new hints, Ed had a discussion with Captain Hughes. However, he was ultimately killed by Envy (Kanata Hongo) after he figured out the hints and informed Captain Mustang (Dean Fujioka) after an altercation with Lust (Yasuko Matsuyuki). Tucker, who was arrested due to illegal practices of Alchemy on his family, escaped and reached the place before Ed and his team could. But before he could set off the reactions, he was killed by Lust, and Hakuro stepped in to finish the experiment, only to unleash an army of Homunculi. He was killed by his army, and it fell on Ed and his team to now save the entire world from these Homunculi. Captain Mustang successfully killed Lust and Envy by lighting them on fire, and Gluttony (Shinji Uchiyama) escaped from there. Finally, Ed met with Truth yet again, but he did not exchange the Philosopher's Stone Mustang had handed him after killing Lust. He couldn't bring himself to exchange the Stone for Al and his body parts and set out to find another way.Ed and Al continue on a journey towards the central station, but they meet new characters, one of whom is suspiciously a prince. Prince Ling Yao (Keisuke Watanabe), at first, is curious about the Philosopher's Stone that Ed and Al have either discarded or kept in a safe place. They are challenged to a fight with Ling Yao's bodyguard, and Ed finds himself slipping off the train only to be saved by none other than Envy (Kanata Hongo). Envy, who had previously died, was still alive. After fighting and also trying to save the train from crashing (Ling Yao was on the train to kidnap Colonel Mustang, the flame Alchemist), Ed and Al are rewarded with new guards by Fuhrer President King Bradley (Hiroshi Tachi) due to a serial killer killing all of the State Alchemists one by one. 10 have been killed so far throughout the country. The killer has a large scar on their forehead. While shaking off the guards, Ed and Al get confronted by Scar (Mackenyu), the rumored State Alchemist Killer. Ed almost gets killed but narrowly escapes (when Colonel Mustang comes to his rescue) with his metal hand destroyed. Scar was forced to retreat in face of overwhelming force.13 years ago, an officer killed an Ishvalan tribe child, which started an all-out rebellion. Under the State orders, there was a seven-year-long war with the Ishvalan Tribe, who refused to surrender. They were known for their unique features of red eyes, olive skin, and white hair. The State finally wipes out most of the tribe members by sending the State Alchemists to war as well. The State Alchemists kill without mercy and wipe out the city and homes of many Islavan tribe members. Those who escape are hurt and are treated by Winry's parents, Mr. Yurly (Naohito Fujiki) and Mrs. Sarah Rockbell (Kaoru Okunuki), who are introduced as doctors who would take care of all patients regardless of their origins. They did not care about the alchemists and their mission, instead focusing on ensuring that their patients were taken care of.Meanwhile, one of the State Alchemists found out about Scar and his brother's (Yusuke Ohnuki) hidden group, and he had arrived to handle them. The Alchemist mercilessly used his powers to wreak havoc on the group and kill them off, destroying every single building in sight. Scar had died, but his brother was left alive. Scar's brother was studying Alchemy himself in secret. He had given his research book to Scar. Scar's elder brother could not take the fact that his younger brother had lost his arm and also his life; therefore, he used the recovery rune to exchange his life and arm with his brother.Later, Scar woke up in the hospital with a huge star scar on his forehead as proof of the rune his brother had performed to bring him back. Disoriented and focused more on hate for the people who took away his own brother from him, Scar killed the nearest Amestrians, Winry's parents, for revenge. Scar then set out on the warpath to take his revenge on all of the State Alchemists involved in that war and was later hired after the war. His notion was that all alchemists hired by the State were either inhuman or evil; therefore, they would be better off dead.Edward, on his way to Winry to fix his arm after Scar destroyed it, stopped by his mother's grave, where surprise, he met his absent father Van Hohenheim (Seiyo Uchino), who simply popped up after so many years. It seems like a set-up, when Ed's father leaves giving a warning that the current Kingdom will be destroyed like the legendary city of Xerxes which vanished overnight.Ed travels to ruins in the desert which are supposed to be from the city of Xerxes. There he finds Ishvalan survivors. Amongst this, Ed learns that Scar had killed Winry's parents. Ed returns to Central and tells Alphonse that they need to capture a Homunculus to learn more about the impending catastrophe as prophesied by Ed's father. Ed makes a pact with Ling Yao as they chase the Homunculi and lure out Scar to capture him. Ling Yao says that he is a Prince of the Xing dynasty and is searching for the secret to immortality to stake his claim to the throne, among 40 other princes and princesses. They finally capture Scar and Gluttony. Ed confronts Scar about killing the innocent Rockbell doctors, which Winry overhears. Winry is about to shoot Scar, when Ed stops her allowing Scar to escape. Ed and Alphonse still manage to capture Scar until May (Monroe Ron) intervenes and takes him away. Ling Yao captures Gluttony with the help of Ed. May treats Scar's bullet wound with the Purification Arts.It is revealed that Ed's father is also the father of all the Homunculi, which is later insisted upon when a person with blonde hair is seen rejuvenating using the Stone fragments and commanding Bradley. Bradley says that they can use Colonel Mustang to open the portal. Bradley is also a Homunculus, which is revealed when his eye patch is off, and the tattoo of Ouroboros is visible on his hidden eye. Ed and Al's father seem to be Homunculi as well, who seems to be in-charge of and is also called Father by both Gluttony and Envy.Envy was brought back to life, even when he was clearly killed by Mustang's repeated flame attack in the first movie. However, he did not die as Lust due to the Stone his life was attached to being left intact, whereas Mustang took Lust's Stone while she was dying to give it to Ed, thus successfully killing her. Envy seemed to undergo a personality change in the period following the death. Because he could have been floating between realities and Gluttony had escaped seeking help from his father, Envy could have been brought back by them and also gone through a strict lesson on acting out and putting the sacrifice in danger. He was warmer and saved Ed one too many times. However, Ed and Al seem to be sacrificing for something bigger.Alphonse finds May in the market and follows her to a ruin where she had hidden Scar. Ed and Alphonse realize that May is a royal, and a rival of Ling, vying for the crown. As Ed and Alphonse attack Scar, Winry comes there with Mustang. Winry forgives Scar and says that there must be a reason that her parents saved Scar. This is when the Homunculi arrive at the ruin, who had also helped Gluttony escape.Edward, Ling Yao, and Envy get swallowed by Gluttony by accident. Envy ordered Gluttony to swallow Ling Yao so as to get rid of him. However, Edward jumped in to save him, and Envy jumped in to save Edward because Edward was supposed to be some kind of a sacrifice and was not to be swallowed. This was a strict order issued by their father that the Homunculi were under. However, they got swallowed and got stuck inside Gluttony. Gluttony is supposed to be a mock version of the portal of Truth that Edward was already familiar with. The person the Homunculi called father tried numerous ways to create that portal; however, he failed and got stuck with Gluttony's abysmal portal, which had no exit. Even though Envy was being helpful until this moment, the characters had to go and provoke him, which led Envy to turn into a massive dinosaur-like monster to fight them.